Cortisol Saturation Index
Assessment Protocol
This tool calculates your HPA-axis dysregulation severity and determines the therapeutic Affron® dose required for cortisol normalization. Based on validated clinical markers.
How many years have you experienced persistent stress, anxiety, or burnout?
Mild — waistline change since stress onset
Rate your sleep quality (1 = restful, 5 = waking at 3–4 AM, unrefreshed)
Works normally — how your body responds to caloric restriction
Methodology Note
The Cortisol Saturation Index is derived from validated HPA-axis dysregulation markers including chronic stress duration, visceral adiposity progression, circadian cortisol disruption, and metabolic resistance patterns. Deficit calculations are based on the Affron® clinical trial protocol (88.5mg/day, IRB-registered). Session ID: 216FD6D7 · April 6, 2026. This tool is provided for educational purposes and does not constitute medical advice.



